The first human growth hormone research theory states that the problem in
releasing the dormant Human Growth Hormone in our body lies with somatostatin,
the natural inhibitor of growth hormone.
Somatostatin has been found to increase with age and may act to block the
pituitary's release of growth hormone. When hgh researchers eliminated somatostatin
production in old rats, they found human growth hormone secretion to be as
great as those of young rats.
A second human growth hormone research theory is that the precursor hormone, growth hormone-releasing hormone (GH-RH), which stimulates human growth hormone release by the pituitary gland, becomes less sensitive to signals from the hypothalamus. As a result, insufficient GH-RH is released, resulting in a decrease of human growth hormone secretion over time.
A third human growth hormone research theory is that, not only does human growth hormone secreted and available to receptors in our cells decrease with aging and cause diminished longevity and life extension, but that the cell receptors become more resistant and less responsive to the human growth hormone available. According to this hgh research theory, aging can be viewed as a disease of human growth hormone resistance within our cell receptors similar to the way in which diabetes is a disease of insulin resistance.
The Human Growth Hormone exerts its effect by binding to a single-chain plasma transmembrane glycoprotien receptor. The highest concentration of hgh receptors are found in the liver, adipose tissue, heart, kidneys, intestine, lungs, pancreas, cartilage, and skeletal muscle. This may help to explain a lot of the incredible benefits associated with increasing human growth hormone secretion in the body. As Human Growth Hormone secretion increases all the above body parts are enhanced. Human growth hormone circulates bound to plasma proteins known as growth hormone binding proteins GHBP) At physiologic concentrations, approximately 50% of Hgh Growth Hormone is protein bound. Clearance occurs rapidly through the kidneys, liver, or target tissue, with an average half life of 10-20 minutes
Also see
In
Search For the Fountain of Youth - The History of human growth hormone
Human Growth
Hormone Research Testing - What the professionals are saying about Hgh
Which
Hgh Products are best and why?
